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When infused locally phentermine Alesse preferentially increased extracellular DA whereas fenfluramine selectively Alesse increased extracellular 5-HT. Local administration of chlorphentermine or the PHEN/FEN Alesse mixture caused parallel elevations of both transmitters. Analogous results were obtained when the drugs were injected systemically. Phentermine stimulated robust Alesse locomotor activity in Alesse mice whereas chlorphentermine and fenfluramine Alesse did not. Alesse Alesse PHEN/FEN caused modest locomotor stimulation after a low dose Alesse but Alesse had no effect at the Alesse Alesse highest dose. Accumulating evidence suggests that Alesse chronic drug and alcohol abuse is associated with accumbens of conscious freely Alesse moving rats. A series of amphetamine derivatives Alesse including phentermine chlorphentermine fenfluramine and Alesse PHEN/FEN (1:1 Alesse ratio) were infused Alesse locally into the Alesse accumbens Alesse via Alesse reverse-dialysis (1 10 Alesse 100 M) or injected systemically (1 mg/kg Alesse ip). Dialysate samples were assayed for dopamine (DA) and serotonin (5-HT) by high-performance Alesse liquid chromatography with Alesse electrochemical detection. When infused locally phentermine preferentially increased extracellular DA whereas fenfluramine selectively increased extracellular 5-HT. Local administration of chlorphentermine Alesse or the PHEN/FEN mixture caused parallel elevations of both transmitters. Analogous results were obtained when the drugs Alesse were injected systemically.

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